Pharmacology non steroidal anti inflammatory drugs

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  • dose appropriately
  • pick the right drug and formulation?
    • Choose Cox-2 selective.
    • enteric coating (., aspirin) - a little protection, variable absorption
    • buffers (., aspirin) - a little protection, enhanced absorption
  • GI Protection?
    • PGE 2 analog - Misoprostol ® (Good evidence of efficacy)
    • Protectants (sucralfate) - no clear evidence
    • Omeprazole - no clear evidence
    • Cimetidine et al. - do not appear to be particularly effective for prevention.

Pharmacology non steroidal anti inflammatory drugs

pharmacology non steroidal anti inflammatory drugs

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